Life Sciences

Life SciencesCompany Background
This Organization is a research-oriented, multinational, pharmaceutical company. It strives to benefit patients “by providing new and improved treatments for diseases and their symptoms” and “seeks to continually develop and sell new, high quality, innovative, pharmaceutical preparations, which, together with clinical data and medical education, create new value for patients and the health care system”. The Organization is engaged in the “research, development, marketing, sales and distribution and licensing of prescription pharmaceuticals, over-the-counter medications, and hospital products.”

Objectives
This Organization has an application that was written in-house. This complex package was developed to perform safety and efficacy analysis on their drugs for reporting to the FDA. This system was designed to track the multitude of information collected for such rigorous analyses. After writing their own complex application, the Company realized that their forte and future development was not in designing software. They decided to outsource the support of this system. They needed an organization that would be able to learn their existing application and support their needs in the United States, England, Canada, and Germany.

Resolutions
Destiny’s personnel were trained by the Organization’s software developers in the United States who, in turn, went back to the different countries to support local offices in the use and enhancement of the application. “Once we learned how their system was written and how it works we started supporting them at all their different global locations.”

Benefits
The Organization achieved its goal. It no longer has to support its complex application system in-house. This results in cost savings where they no longer have to dedicate in-house resources to support and maintain the system. In addition, the Organization has the convenience of communicating with one single point of contact in the United States, while support is provided to multiple global locations.
Additional Projects


Company Background
A Large fortune 500 privately held pharmaceutical company founded by physicians more than 60 years ago. They are committed to improving patients’ lives in meaningful ways by providing safe and effective therapies along with educational tools that support their proper use.

Objective
Two longitudinal studies for congestive heart failure were conducted over a ten-year period. The first trial involved a three-arm comparison of vasodilator drugs against a placebo. The winning therapy was then compared in a second trial with the next generation of drugs, ace inhibitors. shutterstock_163946831The responsibilities of these trials were from CRF design through final statistical analysis. The data processing involved database design, data cleaning, safety reporting, efficacy reporting, and mortality analysis.

Resolution
Destiny has been supporting this Organization for several years with various training and consulting projects. Since all of their data was collected on a mainframe environment, they were faced with implementing updated processes to help them exploit the distributed capabilities and features of the Windows operating system. They needed assistance in building Client Server applications. We set up customized training classes for the Company’s employees to teach them the benefit of client server processing as it runs in a Windows/NT environment. They learned how to communicate with other programs using DDE and ODBC technology. Mainframe production jobs that processed their data needed to be able to communicate with the Windows/NT environment. We consulted with them to set up spawners in a DHCP environment that would allow mainframe batch jobs to run and automatically deliver the data to the Windows/NT environment for further processing.

Benefits
This technology has helped them leverage their investment in a client server and distributed environment to better process their data and compete in the pharmaceutical industry.


Life SciencesCompany Background
A Large Fortune 500 Pharmaceutical Company that develops and produces medications and vaccines, for a wide range of medical disciplines. These disciplines include but are not limited to, immunology, oncology, cardiology, endocrinology, and neurology.

Objective
This Company had nightly updates of their patient data and case reports that needed to be published on the web utilizing HTML and PDF files with bookmarking capabilities. This was necessary, as the FDA was moving towards the acceptance of PDF files with bookmarking for electronic submissions. There was no system in place to achieve these results and it was a manual and time-consuming process.

Resolution
Destiny introduced the company to automated software products that could efficiently complete publishing tasks. Destiny guided them through the use of the new software to automate this process where they could have up to the minute reporting and dynamic web pages that could be used by investigators and data managers to better track case report form data and the latest information on their studies.

Benefits
This Company could now have up to the minute reporting and patient data published for use of investigators and data managers, allowing them to continue, develop and produce new medications, eliminating time spent on manual web publishing and processing.


Company Background
A Large Fortune 500 Global BioPharma Company firmly focused on its mission to discover, develop, and deliver innovative medicines to patients with serious diseases

shutterstock_272295968Objectives
This Company was in the midst of a comparison study between two of their drug trails. They needed a way to quickly and efficiently analyze their data, specifically targeting details about safety and effectiveness of each prescription drug. . The Company created both of these protocols at different times and was interested in comparing the results of the two drugs.

Resolutions
Destiny assisted in creating statistical programs to analyze safety and efficacy data during their Ceftazadine/Cefepime comparison study. We were responsible for creating tabular reports and models for the use of the statisticians.

Benefits
The Company was able to determine comparative results from each of their developed prescription drug trails. This allowed them to move forward and continue to develop new innovated medications for patients in need, reducing the need for long analysis and comparison.